HIF1α, Acute Cobalt Toxicity, and Lung Inflammation—Reply

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Title: The Role of Hypoxia Inducible Factor 1α (HIF1α) in Modulating Cobalt-Induced Lung Inflammation Authors:

Hypoxia plays an important role in development, cellular homeostasis, and pathological conditions, such as cancer and stroke. There is also growing evidence that hypoxia is an important modulator of the inflammatory process. Hypoxia inducible factors (HIFs) are a family of proteins that regulate the cellular response to oxygen deficit and loss of HIFs impairs inflammatory cell function. There i...

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ژورنال

عنوان ژورنال: Toxicological Sciences

سال: 2010

ISSN: 1096-6080,1096-0929

DOI: 10.1093/toxsci/kfq249